Enzyme Technology
Kaneka has developed an extensive original enzyme library (wild type) as the result of many years of enzyme research and customer project collaboration. The most proven and useful enzymes from our enzyme library form the basis of what is called the “mutant enzyme library (Smart Library) E which retains enzymes that have been modified to possess a range of reactions.
We are able to carry out screening for the optimal enzyme for the customer’s substrate from our original enzyme library and mutant enzyme library (Smart Library), and develop a scalable and robust enzyme process using the target enzyme.
Kaneka’s Enzyme Library expanded with Smart Library
- Keto reductase
- Ene reductase
- Imine reductase
- D-Amino acid dehydrogenase
- L-Amino acid dehydrogenase
- R-Transaminase
- S-Transaminase
- Amidase
- Esterase
- Imidase
- Lipase
- Hydantoinase
- Decarbamoylase
- Acylase
- Succinylase
- D-amino acid oxidase
- Racemase
- Cofactor recycling enzyme (GDH, FDH)
- etc
What is Smart Library?
Effective Reshaping Active Center of Enzymes
Kaneka’s Biotransformation Platform (Example)
- Chiral Alcohol
- Chiral Amine
- Unnatural Amino Acid
- 3-Substituted 𝝪-Amino Acid
- Quaternary Amino Acid
- C=C double bond reduction
