Human MAb Generation

Kaneka offers technology solutions for monoclonal antibody (MAb) generation. In 2007, Kaneka initiated a MAb discovery program under a strategic alliance with Evec Inc., a Japanese bio-venture that has developed unique technologies to generate “fully human MAb” isolated from human peripheral B-lymphocytes. The Kaneka/Evec alliance provides pharmaceutical companies with “fully human MAb” from Evec's pipeline and a unique R&D collaboration to discover customer's desirable “fully human MAb.”

Please contact Kaneka for more business details.


Evec's MAb Generation Technologies

Evec's key technology is human MAb generation using the Epstein-Barr virus (EBV) transformation. Evec has also specialized technologies to isolate new Human MAbs from the human B-lymphocytes immortalized by EBV infection. Please visit to the Evec's website for technical details and/or contact Kaneka.

Available Services

(1) Pipeline MAbs
     (License & Collaboration)

Evec has already generated human MAbs with high affinity and will continually find new human MAbs under the R&D alliance with Kaneka. The MAbs listed below are available for licensing.

- Human CMV* MAb
- Human GM-CSF** MAb
- Human Midkine MAb

     * CMV: cytomegalovirus
     ** GM-CSF: Granulocyte-Macrophage
         colony-stimulating factor

(2) MAbs on demand
     (R&D Collaboration with Customer)

Under the Kaneka/Evec R&D alliance, Kaneka also offers a collaborative discovery research to meet customer's specific demands, e.g. a new MAb corresponding to specific antigens. We are pleased to discuss the most appropriate collaboration framework for MAb generation.





Asia

KANEKA CORPORATION
QOL Division
3-2-4, Nakanoshima Kita-ku
Osaka 530-8288, Japan
Tel: +81-6-6226-5377
Fax: +81-6-6226-5128
e-mail:pd@fc.kaneka.co.jp

North America

KANEKA AMERICA LLC
QOL-Fine Chemicals
546 Fifth Avenue, 21st Floor
New York, NY 10036, USA
Tel: +1-212-705-4390
Fax: +1-212-705-4350
e-mail:
finechemicalsinfo@kaneka.com

Europe

KANEKA PHARMA EUROPE N.V.
Fine Chemicals Division
Triomflaan 173
1160 Brussels, Belgium
Tel: +32-2-663-0340
Fax: +32-2-663-0361
e-mail: finechem@kaneka.be